Prognostic significance of ubiquitin-specific protease 22 (USP22), and stress-induced phosphor-protein-1 (STIP-1) expressions in papillary thyroid carcinoma; an immunohistochemical study
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چکیده
منابع مشابه
The Expression of FOXE-1 and STIP-1 in Papillary Thyroid Carcinoma and Their Relationship with Patient Prognosis
Background and Objective: Most patients with papillary carcinoma of the thyroid gland (PTC) have favorable outcome, but since it has severe capability to invade the nearby tissues, there is a great risk of regional and distal lymph-nodes (LNs) metastases related to poor prognostic parameters, early recurrences, and distant metastasis that lead to bad patient outcome. ...
متن کاملcd56, hbme-1 and cytokeratin 19 expressions in papillary thyroid carcinoma and nodular thyroid lesions
background: carcinomas of the thyroid follicular epithelium are the most common cancers of the endocrine system. in the diagnosis of thyroid nodules and tumors, the gold standard is histological evaluation. in cases which have morphological overlap,immunohistochemistry is needed for differential diagnosis. the purpose of this study is to investigate the expressions of cd56,hbme?1, cytokeratin 1...
متن کاملTargeting ubiquitin-specific protease 22 suppresses growth and metastasis of anaplastic thyroid carcinoma
Ubiquitin-specific protease 22 (USP22) aberrance has been implicated in several malignancies; however, whether USP22 plays a role in anaplastic thyroid carcinoma (ATC) remains unclear. Here, we report that USP22 expression is highly elevated in ATC tissues, which positively correlated with tumor size, extracapsular invasion, clinical stages, and poor prognosis of ATC patients. In vitro assays s...
متن کاملPAPILLARY THYROID CARCINOMA IN MASHHAD
Thyroid cancer is the most common endocrine malignancy. This study surveys the pathologic characteristics of thyroid cancerin Mashhad and study of papillary carcinoma in more detail. In this retrospective study, 108 out of 197 cases of thyroid cancer were papillary in type (55%), with female to male ratio of 1.91 which is lower than current reports. The age at the time of diagnosis ranged ...
متن کاملStudy of correlation between vascular endothelial growth factor receptor and some prognostic factors in papillary carcinoma of thyroid gland
Background and Objective: Thyroid cancer is the most frequent endocrine malignancy in the world and papillary carcinoma is the most frequent thyroid carcinoma. Different markers used for determination of prognosis and VEGFR is one of them. The aim of present study was to determine the expression of Vascular Endothelial Growth Factor Receptor (VEGFR) as a prognostic marker in papillary carcinoma...
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ژورنال
عنوان ژورنال: Advances in Cytology & Pathology
سال: 2018
ISSN: 2573-2862
DOI: 10.15406/acp.2018.03.00058